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Bottom Mounted Agitator

Fermenter (BMAF)


Fermentation is not just Mixing. It is the precise control of the micro-environment. Whether you are running an aggressive aerobic process requiring high gas dispersion rates or a strictly anaerobic cultivation demanding perfect homogeneity, the bio-m® BMAF Series is the chassis upon which your process stability rests.

From Pilot to Industrial Production. We scale with your biology. The series spans from the BMAF 30 (Pilot Scale) to the massive BMAF 20,000 (Industrial Scale).

We Don't Guess. We Calculate. In fermentation, "off-the-shelf" is a risk you cannot afford. Fit-for-purpose optimization is always included in our scope. Every BMAF project begins with pre-engineering advice. We analyze your specific rheology, gassing rates (vvm), and shear sensitivity to design the exact shaft length, impeller spacing, and hub connection required to maximize your yield.

Advantages

The Advantage of Optimized  Parameters

In fermentation, standard dimensioning provides a safety baseline, but it rarely achieves peak efficiency. We take the engineering further.

By fine-tuning the complete range of agitator parameters—from geometry to positioning—we align the equipment perfectly with your specific process dynamics.

The Value:This subtle optimization yields superior performance on what matters most: your biological yield. It often allows us to achieve these results with a leaner, more efficient drive configuration, reducing your energy footprint and capital expenditure without compromising process capability. 

 Stability in High Aspect Ratios

Fermentation involves long shafts operating in demanding, high-turbulence environments. In these high-aspect-ratio vessels, stability is the prerequisite for performance.

The Liquitec Standard:We ensure operational smoothness through calculation, not estimation. For every BMAF, we model the critical speed thresholds relative to the shaft dimensions and bearing reinforcement.

The Result:Uncompromising rotational stability. We deliver energy to the fluid, ensuring that the mechanical seal and tank bottom are protected from vibration, even during aggressive agitation.

Integrity of the Connection

The interface between the shaft and the impeller is critical for both sterility and mechanics. We offer two definitive solutions based on your operational philosophy.

The Permanent Solution (N5 - Welded Hub): The impeller is fully welded to the shaft no 2. This creates a single, continuous stainless steel unit with zero crevices, offering the ultimate hygienic standard for dedicated GMP processes.

The Flexible Precision (N2 - Sealed Slide Hub): A precision-engineered peel-on connection sealed with O-rings. This design utilizes a tight tolerance fit for mechanic rigidity while ensuring a verified sterile boundary. It offers the ideal balance: the flexibility to reconfigure impellers o demand without compromising hygienic integrity.

Torque Authority

In aerobic processes, gas introduction changes the fluid density, creating resistance that challenges standard magnetic couplings.

The Calculated Solution:We address this physics challenge with precision. By calculating the exact torque curve require for your maximum aeration rates, the BMAF delivers uninterruptible torque transmission. We ensure that your mass transfer KLa is limited only by your biology, never by the capability of the drive train.

The Impeller Arsenal: Beyond the Standard
We do not force your biology to adapt to a limited catalog. We offer a comprehensive
suite of impeller geometries, each engineered for a specific rheological purpose.
Gas Dispersion (High Mass Transfer)
For aggressive aeration, we deploy the Rushton Turbine (RT) or the Hollow Blade (HB). These radial flow masters are designed to shear gas bubbles into micro-bubbles, maximizing the interfacial surface area for oxygen transfer.
Axial Flow & 
 Homogeneity 
To conquer stratification in tall tanks, we utilize the Hydrofoil Propeller (TR) or our High Efficiency Impeller (HEI). These generate powerful top-to-bottom turnover with minimal power consumption
Gentle 
 Cultivation 
For shear-sensitive cell lines, the Marine Propeller (MP) or Segment Impeller (SR) provides the necessary suspension with the lowest possible hydromechanical stress.
Universal 
 Mixing 
The Pitched Blade Impeller (SBR) remains a robust workhorse for general mixing tasks.
Universal 
 Mixing 
 The Pitched Blade Impeller (SBR) remains a robust workhorse for general mixing tasks.

Digital Verification (CFD)


For critical investments, hope is not a strategy. We offer Computational Fluid Dynamics (CFD) simulation as an optional service. Before steel is cut, we simulate the flow patterns, shear gradients, and mixing times inside your specific vessel geometry. This digital twin validates your design, ensuring that the hardware we build will perform exactly as predicted.

Surface Perfection as Standard

In a bioreactor, the surface is part of the sterile barrier. We standardize on excellence. Our default offering for wetted parts is a surface roughness of Ra < 0.4 µm, finished with Electropolishing (E2). This ultra-smooth profile minimizes biofilm adhesion and maximizes corrosion resistance, ensuring your CIP & SIP cycles are effective every time.

Comprehensive Validation
​We deliver more than a machine; we deliver a compliant component of your GMP
audit trail. Every BMAF comes with a complete validation package, including:

  • Material Certificates (3.1) for all product-contact parts

  • Certified Surface Roughness Reports
  • Delta Ferrite Content Verification​
  • FDA / USP Class VI compliance for all seals.

Flange Integration


Defined by Access

We align the mechanical interface with your maintenance philosophy.

The Hermetic Standard
(F1 - Weld-In Can)

The containment shell is welded directly into the vessel bottom. Zero gaskets, zero crevices—the permanent choice for dedicated lines.

The Serviceable
(F2 - Plug-In Can)

Ideal for vessels without hand-hole access. This design allows the containment shell to be removed from the outside, permitting seal maintenance without ever breaching the sterile tank boundary.

How to Order bio-m® Bottom Mounted

Agitator Fermenter

bio-m® BMAF Bottom Mounted Fermenter Agitator can be selected based on your application, vessel volume, viscosity, mixing task, surface and material. A custom made piece of equipment to perfectly fit your process.

Request more information

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